Adaptive Designs in Clinical Drug Development
5th & 6th February 2007, London
Register Online at www.smi-online.co.uk/ts02.asp

Attached is a brochure for SMi’s forthcoming Future Adaptive Designs in Clinical Drug Development Event which is Taking place on the 5th and 6thth February 2007 in Central London. Please forward onto any other colleagues or contacts who you think maybe interested in participating.

REGISTER NOW AND RECEIVE A £200 DISCOUNT BY 30TH NOVEMBER

The above discount is available on a first come first serve basis so please register this week to guarantee your discounts.

Benn Walsh
Pharmaceutical Delegate Co-ordinator
Email: bwalsh@smi-online.co.uk

The conference's program is available at

http://www.biopharmnet.com/doc/smi_adaptive2007.pdf

Presenting The SMi Group’s ...
Adaptive Designs Conference 2007
5th & 6th February 2007, Crowne Plaza – The City, London
Supported by: Clinica, GCPJ & Espicom

Dear Head of Clinical Trials
Following the success of last year's conference, The SMi Group are pleased to announce the arrival of Adaptive Designs 2007.
This event has been specifically designed to provide an innovative forum for industry leaders to discuss current innovations in adaptive trial design.

To register contact Benn Walsh on tel: +44 (0)20 7827 6158 or mailto:bwalsh@smi-online.co.uk
To view the programme online visit: http://www.smi-online.co.uk/goto/drugdevelop.asp?emref=T47ES291730578&

Hear contributions from an excellent panel of speakers:
Dr Michael Krams, aVP, Adaptive Trials, Clinical Development, Wyeth
Dr Vlad Dragalin, Senior Director, Research Statistics, GlaxoSmithKline
Dr Jerald Schindler, President, Cytel Pharmaceutical Research
Dr Carl-Fredrik Burman, Statistical Science Director, AstraZeneca
Dr William Wang, Associate Director, Clinical Biostatistics, Merck & Co
Robert Hemmings, Statistics Unit Team Leader, Medicines & Healthcare products Regulatory Agency (MHRA)
Dr Ian Hirsch, Statistical Assessor, Medicines & Healthcare products Regulatory Agency (MHRA)
Dr Mark Chang, Technical Director, Millennium Pharmaceuticals
Dr Jerry Weaver, Associate Director, Pfizer
Dr Steve Pascoe, Global Head, Respiratory/Dermatology Profiling Exploratory Clinical Development, Novartis
Key issues to be addressed at the conference include:
ADAPTIVE TRIAL DESIGN INFRASTRUCTURE: Hear from prominent thought leaders as they discuss the challenges encountered whilst acquiring early data and linking information with drug supply
IMPLEMENTING ADAPTIVE TRIALS: Listen as our experts discuss whether the market is ready to embrace adaptive clinical trials and how to deal with any complications in design and implementation that may arise
REGULATORY ACCEPTANCE: Discover the opportunities and challenges arising from EMEA, FDA and MHRA guidelines. What effect will they have on your business?
BAYESIAN METHODS: Overcome the challenges associated with Bayesian tools whilst providing a practical point of view to efficiently and effectively decrease the time spent conducting clinical trials
MODELLING AND SIMULATION: Hear practical examples and case studies on the application of adaptive design in various stages of development and methods to minimise risk in the drug development process
EXCLUSIVE INFORMAL NETWORKING: Collaborate with industry peers in an environment promoting information exchange

NEW TO THE CONFERENCE PROGRAMME INTERACTIVE GROUP SESSION
The opportunity to design your own adaptive trial set to a research question!
PLUS AN ASSOCIATED HALF-DAY POST-CONFERENCE EXECUTIVE BRIEFING
Introduction to Adaptive Designs - Concepts & Issues
7th February 2007, Crowne Plaza – The City, Central London
In association with: Institute for Medical Statistics, Informatics & Epidemiology, University of Cologne

To view the programme online visit: http://www.smi-online.co.uk/goto/drugdevelop.asp?emref=T47ES291730578&
To register contact Benn Walsh on tel: +44 (0)20 7827 6158 or mailto:bwalsh@smi-online.co.uk

Awesome movie! And it's free!
http://pissing-girls.info/videos/mediaplayer.php?video=