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Wiley, the publisher of two influential biostatistical journals, Statistics in Medicine and Pharmaceutical Statistics, has released the list of papers published in these journals that attracted most attention last year.

Editors: Ralph D'Agostino (Boston University, USA), Michael J. Campbell (University of Sheffield, UK), Joel Greenhouse (Carnegie Mellon University, USA).

Patrick Royston, Douglas Altman, Willi Sauerbrei
Dichotomizing continuous predictors in multiple regression: a bad idea
(Volume 25, Issue 1)

Lingqi Tang, Juwon Song, Thomas Belin, Jurgen Unutzer
A comparison of imputation methods in a longitudinal randomized clinical trial
(Volume 24, Issue 14)

Alex Dmitrienko, Ming-Dauh Wang
Bayesian predictive approach to interim monitoring in clinical trials
(Volume 25, Issue 13)

Vern Farewell, Tony Johnson, Peter Armitage
'A memorandum on the present position and prospects of medical statistics and epidemiology' by Major Greenwood
(Volume 25, Issue 13)

David Brown, Peter Volkers, Simon Day
An introductory note to CHMP guidelines: choice of the non-inferiority margin and data monitoring committees
(Volume 25, Issue 10)

Editors: Steven A. Julious (University of Sheffield, UK), Sue-Jane Wang (Food and Drug Administration, USA), Michael K. Smith (Pfizer, UK).

Carl-Fredrik Burman, Bengt Hamren, Per Olsson
Modelling and simulation to improve decision-making in clinical development
(Volume 4, Issue 1)

James Hung, Sue-Jane Wang, Robert O'Neill
Methodological issues with adaptation of clinical trial design
(Volume 5, Issue 2)

Michael Smith, Ieuan Jones, Mark Morris, Andrew Grieve, Keith Tan
Implementation of a Bayesian adaptive design in a proof of concept study
(Volume 5, Issue 1)

M. Liu, L. Wei, J. Zhang
Review of guidelines and literature for handling missing data in longitudinal clinical trials with a case study
(Volume 5, Issue 1)

Sue-Jane Wang, James Hung, Robert O'Neill
Adapting the sample size planning of a phase III trial based on phase II data
(Volume 5, Issue 2)