Main page > Software > Code Depot

This topic is managed by the Cardiac Safety Advisory Board (Alex Dmitrienko).

This page includes links to papers on cardiac safety issues/QTc prolongation in clinical trials.

If you would like to contribute to the Code Depot project, the Cardiac Safety Advisory Board encourages you to post relevant information in this discussion thread in the BioPharmNet forum.

Zhang, L., Dmitrienko, A., Luta, G. (2008). Sample size calculations in thorough QT studies. Journal of Biopharmaceutical Statistics. 18, 468-482 [SAS code].